Innovation Capabilities & Products
- Patent | Myticin peptide and its use in cell regeneration
Authors: Antonio Figueras Huerta, María Gasset Vega, Beatriz Novoa García, Magalí Rey Campos, Ricardo Mallavía Marín, Regla María Medina Gali, Alicia Martínez López
The present invention relates to peptides derived from myticin C and to their therapeutic use, more specifically in cell and/or tissue regeneration. More detailed information can be obtained here.
- Patent | Andrographolide derivatives for their use in the treatment of cytokine-related inflammatory diseases
Authors: Eva María Rivero Buceta; Cristian Smerdou Picazo; Pablo Botella Asunción; Antonio Pineda Lucena; Carla María Vidaurre Agut; Beatriz Novoa; Antonio Figueras Huertas; Jose María Benlloch Baviera
Andrographolide derivatives for their use in the treatment of cytokine-related inflammatory diseases . Patent pending publication.
- Patent | Andrographolide derivatives for their use in the treatment of COVID-19 and associated pulmonary fibrosis
Authors: Antonio Pineda Lucena; Carla María Vidaurre Agut; Eva María Rivero Buceta; Jose María Benlloch Baviera; Cristian Smerdou Picazo; Beatriz Novoa; Antonio Figueras Huertas; Pablo Botella Asunción
Andrographolid derivatives for their use in the treatment of COVID-19 and associated pulmonary fibrosis. Patent pending publication.
- Patent | Method for the identification of antimicrobial polypeptides in Mytilus edulis
Authors: María del Mar Costa Portela, Beatriz Novoa García, Antonio Figueras Huerta, Sonia Dios Vidal, Camino Gestal Mateo
The invention provides a method for the identification of polynucleotides, coding precursors of polypeptides, with antibacterial and antiviral activity (myticines and mytilines). More detailed information can be obtained here.
- Capabilities | Generation and supply of zebrafish mutants
Generation of stable zebrafish mutant and transgenic lines to use as model systems to study fish and human diseases.
- Capabilities | Development of “in vivo” bioactivity tests for biomolecules using animal models
Use of animal models (zebrafish, turbot, mice, etc.) as model systems to study the bioactivity of different compounds, as well as fish and human diseases (septic shock, inflammatory illnesses, etc.).
- Capabilities | Development of bioindicators for environmental monitoring
Characterization and measurement of micro-physiological responses or molecular markers generated in response to environmental conditions for the development of an early warning system for environmental perturbations.
- Capabilities | Biodiversity AssessmentMarine instruments & sensors Coastal & Environmental Protection Maritime Spatial Planning Ecosystem Services & Governance
Monitoring temporal and spatial distribution of species, abundance and biomass from several taxa using different techniques such as e-DNA, pigment characterization, flow cytometry, acoustic telemetry, images collected from remote observation systems (i.e. drones, etc.) or classic taxonomic identification.
- Capabilities | Advanced -omics applied to marine organisms
Studies on the structure of the genome of marine organisms, including gene mapping, DNA sequencing and how the complete set of RNA transcripts is produced by the genome and affected by development, diseases, or environmental factors conditioning the phenotype and particularly proteomics and metabolomics, always applying the most advanced techniques (ATAC-seq, MethylCap-Seq, RNA-seq, recombinant DNA technology, knockin and knockout CRISPR/Cas9, enhancer detector (ZED),Tol2 kit and BAC transgenic technologies, etc.).
- Capabilities | Development of “in vitro” bioactivity tests for biomolecules using cell lines and specific gene expression tests
Development of techniques (metabolomics, proteomics, genomics, lipidomics, biomarkers) to characterize the response of cells to different biomolecules and to validate their activity and safety.